
If you're after Prague's freshest culinary opening rather than another rundown of tried-and-tested spots, head to the new business district by Masaryk Station. It's there, inside the futuristic Masaryčka building, that the restaurant and brewery Fuze launched in spring 2026 — one of the most talked-about debuts on Prague's dining scene in recent months, bringing together its own in-house brewery, chef-driven cuisine and striking design across three floors.
The concept began with the idea of "fusion" in the broadest sense — bringing together things that don't usually go together. The core idea behind the newly opened Fuze is exactly that: with 320 seats, the restaurant offers guests an enormous range of experiences and flavours, set inside Penty's flagship building on the site of a station that had looked drab for years. The project belongs to the Gare Restaurants group, and according to co-owner Jan Mudroch, it was clear from the start that they wanted to create a place open to everyone — making this the first Gare venue built around volume rather than spend-per-guest. The restaurant officially opened its doors to the public on 3 April, inside the new "radiator" building right next to Masaryk Station.
Fuze's headline feature is its brewery, set right in the dining room and visible through glass. The brewery sits directly inside the restaurant, letting guests watch the brewing process through a glass-walled brewhouse — the only one of its kind in Czechia. The equipment didn't arrive from scratch: to make sure beer culture takes centre stage, Fuze relocated the entire brewing setup from the U Supa brewery. Brewer Aleš Pajk oversees the brewing, while the kitchen serves modern Czech and German cuisine made with premium ingredients only, including American US Prime beef, alongside signature dishes such as Thor's Hammer and the Shrimp Roll. The menu itself is billed as "fused" — the restaurant stands out for its own brewery and a mix of local, Asian and unconventional flavours.
The atmosphere here is far from Prague's cosy traditional pubs — this is a large-scale, almost club-like space. The new venue, with its own small brewery, spans three floors and 1,400 square metres, and once the terrace opens it will be able to seat up to 520 guests. The interior was handled by a design team: Fuze offers a pulsing atmosphere with a quality sound system and a layered interior blending elements from Czech and Slovak artists — the work of architectural studio Pizingers Morix and installations by studio ByAllMeans. The building itself is part of the experience too: the vibrant Fuze occupies three floors of the striking modern Masaryčka building, designed by the studio of the famed Zaha Hadid.
Insider tip: the venue positions itself as an all-purpose spot for any occasion — from business lunches to full-blown parties. This cosmopolitan restaurant in the new Masaryčka building stands out for its own brewery, where local ingredients mix with Asian and other unconventional flavours, so it works well for a daytime working lunch (there's a daily midday menu), while in the evening it's worth lingering at the bar over the house cocktails and homemade lemonades. Booking ahead is recommended — the place has already become a magnet for after-parties following events at the neighbouring Masaryčka office towers.
Address: Na Florenci 2139/2, 110 00, Praha 1 (inside the Masaryčka building, by the Masarykovo nádraží metro station and train station)
Phone/reservations: +420 734 889 633
Fuze is well worth adding to your list if you want to check out Prague's freshest and most ambitious culinary newcomer of 2026: craft beer fans keen to watch the brewing happen right in the dining room, admirers of unusual interiors set inside landmark architecture, and groups looking for a spacious spot for gatherings and parties right in the heart of the city.
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Source: aroundprague.cz
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